"Nous avons démontré qu'un échodopler cérébral pulsé (encéphaloscan) ou plus exactement la tomosphygmographie cérébrale ultrasonore (TSCU) permettait de mettre en évidence objectivement chez les personnes EHS des anomalies de pulsatilité cérébrale, probablement de nature artérielle au niveau des lobes temporaux. Et que cet examen permettait de suivre l'évolution de cette affection chez les malades sous traitement." (Source : Lettre d'information No7 - décembre 2018 - www.ehs-mcs.org - lettre pas encore on-line). Voici le texte intégral en anglais :
Irigaray Philippe1 , Lebar Philippe2 and Belpomme Dominique1,3* 1European Cancer and Environment Research Institute (ECERI), Brussels, Belgium 2Centre de radiologie Lebar Philippe, Paris, France 3Paris V University Hospital, France *Corresponding author: Belpomme Dominique, European Cancer and Environment Research Institute (ECERI), Brussels, Belgium, Paris V University Hospital, France, Phone: +33145785353; E-mail: contact.belpomme@gmail.com
Received date: June 24, 2018; Accepted date: July 11, 2018; Published date: July 15, 2018
Abstract
Although electrohypersensitivity (EHS) is a detrimental health condition officially acknowledged by the World Health Organisation its characterization as a new pathological disorder remains to be clarified. In a prospective bioclinical study of EHS- and/or multiple chemical sensitivity (MCS) self-reporting patients, we used both ultrasonic cerebral tomosphygmography (UCTS) and transcranial Doppler ultrasonography to measure intracerebral pulsations with the aim to further characterize the brain abnormalities in these patients.
In the present study we describe the UCTS imaging technique and report the results obtained by using this technique in 565 EHS and EHS/MCS cases so far enrolled, among which 535 are fully evaluable according to previously established criteria. There were 353 patients with EHS (66%) and 182 with both EHS and MCS (34%). Overall, relative to normal controls the results show a significant decrease (p<0.00001) in the mean tissue pulsometric index (PI) in the middle cerebral artery (MCA)-dependent areas of temporal lobes, predominantly in the capsulo-thalamic and adjacent areas in more than 80% of the patients. Since mean tissue PI decrease in temporal lobes may reflect decrease in MCA brain blood flow and/or neuronal metabolic dysfunction, and the capsulo-thalamic area contains both the limbic system and the thalamus, we suggest these two particular brain structures could be associated with some vascular and metabolic impairment. We conclude that UCTS is a simple ultrasound-based technique that can be used in addition to EHS-related biomarker measurement and other imaging techniques for the diagnosis of EHS in EHS- and EHS/MCS-self reporting patients.
Full text:
https://www.omicsonline.org/open-access/how-ultrasonic-cerebral-tomosphygmography-can-contribute-to-the-diagnosis-of-electrohypersensitivity-2376-0311-1000142.pdf
Copyright: ©2018 Dominique B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received date: June 24, 2018; Accepted date: July 11, 2018; Published date: July 15, 2018
Abstract
Although electrohypersensitivity (EHS) is a detrimental health condition officially acknowledged by the World Health Organisation its characterization as a new pathological disorder remains to be clarified. In a prospective bioclinical study of EHS- and/or multiple chemical sensitivity (MCS) self-reporting patients, we used both ultrasonic cerebral tomosphygmography (UCTS) and transcranial Doppler ultrasonography to measure intracerebral pulsations with the aim to further characterize the brain abnormalities in these patients.
In the present study we describe the UCTS imaging technique and report the results obtained by using this technique in 565 EHS and EHS/MCS cases so far enrolled, among which 535 are fully evaluable according to previously established criteria. There were 353 patients with EHS (66%) and 182 with both EHS and MCS (34%). Overall, relative to normal controls the results show a significant decrease (p<0.00001) in the mean tissue pulsometric index (PI) in the middle cerebral artery (MCA)-dependent areas of temporal lobes, predominantly in the capsulo-thalamic and adjacent areas in more than 80% of the patients. Since mean tissue PI decrease in temporal lobes may reflect decrease in MCA brain blood flow and/or neuronal metabolic dysfunction, and the capsulo-thalamic area contains both the limbic system and the thalamus, we suggest these two particular brain structures could be associated with some vascular and metabolic impairment. We conclude that UCTS is a simple ultrasound-based technique that can be used in addition to EHS-related biomarker measurement and other imaging techniques for the diagnosis of EHS in EHS- and EHS/MCS-self reporting patients.
Full text:
https://www.omicsonline.org/open-access/how-ultrasonic-cerebral-tomosphygmography-can-contribute-to-the-diagnosis-of-electrohypersensitivity-2376-0311-1000142.pdf
Copyright: ©2018 Dominique B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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